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Shotgun Sequencing

Topic

  • Biochemistry & Molecular Biology
  • DNA & RNA
  • Biotechnology
  • Genetics
  • Bioinformatics

Resource Type

  • Videos
  • Animations

Level

High School — GeneralHigh School — AP/IBCollege

Duration

00:01:00
Saved By
9 Users
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Description

This animation illustrates shotgun sequencing, a method that was used to sequence the human genome.

Shotgun sequencing is a technique for sequencing large DNA sequences, such as entire genomes. As shown in the animation, many copies of the genome are first broken into millions of small fragments. After each fragment is sequenced, powerful computers use overlapping sections to assemble the fragments into their original order.

Depending on students’ background, it may be helpful to pause the animation at various points to discuss different parts of the method.

Key Terms

bioinformatics, DNA, genomics, Human Genome Project, laboratory technique, nucleic acid, sequence assembly

Terms of Use

The resource is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International license. No rights are granted to use HHMI’s or BioInteractive’s names or logos independent from this Resource or in any derivative works.

Accessibility Level (WCAG compliance)

Video files meet criteria.

Version History

Date Published 02.05.03

Materials

Large (MOV) 12 MB
Large (WMV) 12 MB
Small (MOV) 6 MB
Small (WMV) 6 MB
Transcript (PDF) 11 KB

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