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Regulation of Eukaryotic DNA Transcription

Topic

  • Biochemistry & Molecular Biology
  • DNA & RNA
  • Genetics
  • Gene Expression & Regulation

Resource Type

  • Videos
  • Animations

Level

High School — GeneralHigh School — AP/IBCollege

Duration

00:02:05
Used In
1 BioInteractive Playlists
Saved By
15 Users
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Description

This animation shows how a variety of proteins interact to regulate the transcription of eukaryotic DNA into RNA.

During transcription, DNA is copied into RNA by an enzyme called RNA polymerase. As shown in the animation, this process involves many different proteins. Some of these proteins are general transcription factors that recruit RNA polymerase to the gene. Other proteins, such as activators, repressors, and mediators, are transcription factors that regulate the action of RNA polymerase.

Depending on students’ background, it may be helpful to pause the animation at various points to discuss different molecules or regions of DNA.

Key Terms

activator, chromatin, enhancer, mediator, promoter, regulator, repressor, RNA polymerase

Terms of Use

The resource is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International license. No rights are granted to use HHMI’s or BioInteractive’s names or logos independent from this Resource or in any derivative works.

Accessibility Level (WCAG compliance)

Video files meet criteria.

Version History

Date Published 02.05.11

Materials

Large (MOV) 17 MB
Large (WMV) 17 MB
Small (MOV) 9 MB
Small (WMV) 9 MB
Transcript (PDF) 12 KB

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