Skip to main content
HHMI BioInteractive
  • Español
  • Site Search
  • Log In/Create Account
  • BioInteractive Resources
  • Planning Tools
  • Professional Development
  • About Us

Mutations in Cancer

Topic

  • Genetics
  • Genetic Disease
  • Mutations
  • Cell Biology
  • Cell Cycle

Resource Type

  • Videos
  • Clips

Level

High School — AP/IBCollege

Duration

00:08:32
Saved By
32 Users
Share This
View in Spanish

Description

This video provides an overview of the types of genes that, when mutated, can lead to the development of cancer.

This video explains the difference between proto-oncogenes, oncogenes, and tumor suppressor genes, and how mutations in these genes drive cancer development. These genes often play important roles in cellular processes, including the cell cycle, DNA repair, and cellular differentiation.

This video is a clip from a 2013 Holiday Lecture on Science, Medicine in the Genomic Era.

Key Terms

cell cycle, cellular differentiation, cell division, cell survival, DNA repair, oncogene, tumor suppressor gene

Terms of Use

Please see the Terms of Use for information on how this resource can be used.

Accessibility Level (WCAG compliance)

Spanish files meet criteria.

Version History

Date Published 09.29.14
Date Updated 06.02.20

Materials

HD (M4V) 225 MB
HD (WMV) 252 MB
SD (M4V) 67 MB
SD (WMV) 64 MB
Spanish Dub (Español) (M4V) 258 MB
Transcript - Español (PDF) 240 KB

Explore Related Content

Other Resources About Cancer

Showing of
Image from the activity
Data Points
Efficacy of a Medication for Chronic Myeloid Leukemia
Image from the activity
Data Points
Cell Division and Cancer Risk
Computer illustration of p53 molecule
Click & Learn
The p53 Gene and Cancer
Image of cancer cells from the activity
Phenomenal Images
Cancer Cell Invasion
Computer image of BCR-ABL
3D Models
BCR-ABL
Computer image of resistant BCR-ABL
3D Models
Gleevec-Resistant BCR-ABL
Computer image of ATP
3D Models
Adenosine Triphosphate (ATP)
Computer image of imatinib
3D Models
Gleevec (Imatinib)
Computer image of dasatinib
3D Models
Dasatinib
Image from the resource
Card Activities
Classifying Cancer Genes and Examining Patient Data
Computer image of BCR-ABL
Click & Learn
BCR-ABL: Protein Structure and Function
Illustration of the phases of the cell cycle
Click & Learn
The Eukaryotic Cell Cycle and Cancer
Photo of Charles Sawyers from the video
Clips
DNA Sequence Technology Improves Cancer Treatment
Computer image of gleevec and BCR-ABL from the video
Animations
Mechanism of a Medication for Chronic Myeloid Leukemia
Computer image of a tumor undergoing angiogenesis
Animations
How Tumors Grow
Computer image of DNA from the video
Animations
DNA Damage and Mutations
Computer illustration of a normal cell from the video
Animations
Using p53 to Fight Cancer
Image of cells and blood supply from the video
Animations
VEGF
Computer image of cell growth from the video
Animations
Cancer and Cell Fate in the Intestinal Epithelium
Computer image of gleevec resistant BCR-ABL from the video
Animations
Resistance to a Medication for Chronic Myeloid Leukemia

Other Related Resources

Showing of
Image of cancer cells from the activity
Phenomenal Images
Cancer Cell Invasion
Computer image of a blood vessel
Animations
Sickle Cell Disease
Image from the resource
Card Activities
Classifying Cancer Genes and Examining Patient Data
Illustration of the phases of the cell cycle
Click & Learn
The Eukaryotic Cell Cycle and Cancer
Image from the activity
Data Points
Cell Division and Cancer Risk
A circle containing round and sickle shapes; a couple are round with irregular edges.
Card Activities
Why Do Some People with the Sickle Cell Genotype Not Have Symptoms?
Computer image of DNA from the video
Animations
DNA Damage and Mutations
A scientific figure from a study that investigated the role of p53 in cell cycle regulation
Data Points
Role of p53 in the Cell Cycle
Computer image of a tumor undergoing angiogenesis
Animations
How Tumors Grow
Computer illustration of crossing over between chromosomes
Animations
Meiosis
HHMI BioInteractive
  • Facebook
  • Instagram
  • Twitter
  • YouTube
  • Newsletter Signup
  • HHMI.org
  • Terms of Use
  • Privacy Policy
  • Accessibility