Learning from Mice: The Science of Transgenic Technology

Topic

Resource Type

Level

High School — GeneralHigh School — AP/IBCollege

Duration

00:11:08
Saved By
7 Users

Description

This video describes two methods for developing transgenic mice to study human genetic diseases.

A transgenic animal carries a foreign gene that has been deliberately inserted into its genome. The video shows two methods for developing transgenic mice. The first method involves injecting the desired gene into the pronucleus of a fertilized mouse egg. The second method involves transforming embryonic stem cells by homologous recombination with the desired DNA.

This clip comes from a 2003 Holiday Lecture Series, Learning from Patients: The Science of Medicine.

Key Terms

genetic engineering, genetically modified organism (GMO), laboratory technique, method, model organism, mutation, oocyte, transgene

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