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Learning from Mice: The Science of Transgenic Technology

Topic

  • Biochemistry & Molecular Biology
  • Biotechnology
  • Genetics
  • Gene Expression & Regulation
  • Scientific Skills & Literacy
  • Experimental Design

Resource Type

  • Videos
  • Clips

Level

High School — GeneralHigh School — AP/IBCollege

Duration

00:11:08
Saved By
7 Users
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Description

This video describes two methods for developing transgenic mice to study human genetic diseases.

A transgenic animal carries a foreign gene that has been deliberately inserted into its genome. The video shows two methods for developing transgenic mice. The first method involves injecting the desired gene into the pronucleus of a fertilized mouse egg. The second method involves transforming embryonic stem cells by homologous recombination with the desired DNA.

This clip comes from a 2003 Holiday Lecture Series, Learning from Patients: The Science of Medicine.

Key Terms

genetic engineering, genetically modified organism (GMO), laboratory technique, method, model organism, mutation, oocyte, transgene

Terms of Use

Please see the Terms of Use for information on how this resource can be used.

Version History

Date Published 02.08.03

Materials

Large (MOV) 84 MB
Large (WMV) 84 MB
Small (MOV) 26 MB
Small (WMV) 26 MB

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