Learning from Mice: The Science of Transgenic Technology

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Resource Type
Level
High School — GeneralHigh School — AP/IBCollege
Duration
00:11:08
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3 Users
Description

This video describes two methods for developing transgenic mice to study human genetic diseases.

A transgenic animal carries a foreign gene that has been deliberately inserted into its genome. The video shows two methods for developing transgenic mice. The first method involves injecting the desired gene into the pronucleus of a fertilized mouse egg. The second method involves transforming embryonic stem cells by homologous recombination with the desired DNA.

Details
Key Terms

genetic engineering, genetically modified organism (GMO), laboratory technique, method, model organism, mutation, oocyte, transgene

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