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Interactive Case Study for Natural Selection in an Outbreak

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A series of illustrations of D-N-A fragments laid out in a 4 by 4 grid.

Topic

  • Genetics
  • Genomics
  • Microbiology
  • Viruses
  • Pathogens & Disease
  • Evolution
  • Natural Selection

Resource Type

  • Interactive Media
  • Interactive Videos

Level

High School — GeneralHigh School — AP/IBCollege
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Description

This interactive video explores how two scientists tracked the 2013 Ebola outbreak in West Africa. 

Geneticist Pardis Sabeti investigated the evolution of the virus over time, whereas epidemiologist Lina Moses investigated the societal factors that contributed to the outbreak. Their experiences illustrate some of the factors that can cause an outbreak to occur and why it is important to curb the spread of infection as rapidly as possible. As students watch the video, they are prompted to answer questions that require them to predict steps in the research process and interpret data. Students also make connections to their own experiences with infectious diseases.

The “Student Worksheet” lists the questions embedded in the video. The “Educator Materials” document provides implementation tips from educators who have used interactive case studies in their classroom. It also provides additional discussion questions and guidance on assessing students’ responses.

The “Resource Google Folder” link directs to a Google Drive folder of resource documents in the Google Docs format. Not all downloadable documents for the resource may be available in this format. The Google Drive folder is set as “View Only”; to save a copy of a document in this folder to your Google Drive, open that document, then select File → “Make a copy.” These documents can be copied, modified, and distributed online following the Terms of Use listed in the “Details” section below, including crediting BioInteractive.

Student Learning Targets

  • Identify some of the factors that can fuel an infectious disease outbreak in humans.
  • Explain how viruses evolve by natural selection during an epidemic.
  • Describe how the evolution of viruses can be studied using their genetic information.
  • Explain why outbreaks should be stopped as early as possible.

Estimated Time

Within one 50-minute class period.

Key Terms

Ebola, epidemic, epidemiology, health profession, healthcare, infection, spillover, zoonotic disease 

Primary Literature

Gire, Stephen K., Augustine Goba, Kristian G. Andersen, Rachel S. G. Sealfon, Daniel J. Park, Lansana Kanneh, Simbirie Jalloh, et al. “Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak.” Science 345, 6202 (2014): 1369–1371. https://www.science.org/doi/10.1126/science.1259657.

Terms of Use

Please see the Terms of Use for information on how this resource can be used.

Accessibility Level (WCAG compliance)

PDF files meet criteria. Interactive media meets criteria.

Version History

Date Published 04.27.23

NGSS 2013

HS-LS3-2, HS-LS4-4; SEP1, SEP6, SEP8

AP Biology 2019

SYI-3.A, IST-1.K, IST-1.O, IST-4.B, EVO-1.D, EVO-1.M, ENE-3.D; SP1, SP6

IB Biology 2016

5.2, 6.3, B.5

Vision and Change 2009

CC1, CC5

Materials

Download Resource Google Folder (Link)
Download Educator Materials (PDF) 449 KB
Download Student Worksheet (PDF) 248 KB
Download Transcript (PDF) 245 KB

Use This Resource With

Video Resource
Think Like a Scientist: Natural Selection in an Outbreak

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