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Human Genome Sequencing

Topic
  • Biochemistry & Molecular Biology
  • DNA & RNA
  • Biotechnology
  • Genetics
  • Bioinformatics
Resource Type
  • Videos
  • Animations
Level
High School — GeneralHigh School — AP/IBCollege
Duration
00:01:49
Favorited By
6 Users
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Description

This animation shows how the Human Genome Project sequenced the human genome, which contains over 3 billion nucleotides.

The Human Genome Project started by identifying unique marker sequences distributed throughout the genome. As shown in the animation, many copies of DNA were then broken into smaller fragments, which were individually sequenced using a method called shotgun sequencing. With the help of the marker sequences, overlapping sections, and powerful computers, the fragment sequences were assembled in their original order.

Depending on students’ background, it may be helpful to pause the animation at various points to discuss different steps in the process.

Details
Key Terms

bioinformatics, DNA, genomics, marker sequence, nucleic acid, sequence assembly

Terms of Use

The resource is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International license. No rights are granted to use HHMI’s or BioInteractive’s names or logos independent from this Resource or in any derivative works.

Version History
Date Published 02.05.03
Materials
Large (MOV) 17 MB
Large (WMV) 17 MB
Small (MOV) 7 MB
Small (WMV) 7 MB
Transcript (PDF) 12 KB

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