Skip to main content
HHMI BioInteractive
  • Español
  • Site Search
  • Log In/Create Account
  • BioInteractive Resources
  • Planning Tools
  • Professional Development
  • About Us

Human Genome Sequencing

Topic

  • Biochemistry & Molecular Biology
  • DNA & RNA
  • Biotechnology
  • Genetics
  • Bioinformatics

Resource Type

  • Videos
  • Animations

Level

High School — GeneralHigh School — AP/IBCollege

Duration

00:01:49
Saved By
9 Users
Share This

Description

This animation shows how the Human Genome Project sequenced the human genome, which contains over 3 billion nucleotides.

The Human Genome Project started by identifying unique marker sequences distributed throughout the genome. As shown in the animation, many copies of DNA were then broken into smaller fragments, which were individually sequenced using a method called shotgun sequencing. With the help of the marker sequences, overlapping sections, and powerful computers, the fragment sequences were assembled in their original order.

Depending on students’ background, it may be helpful to pause the animation at various points to discuss different steps in the process.

Key Terms

bioinformatics, DNA, genomics, marker sequence, nucleic acid, sequence assembly

Terms of Use

The resource is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International license. No rights are granted to use HHMI’s or BioInteractive’s names or logos independent from this Resource or in any derivative works.

Accessibility Level (WCAG compliance)

Video files partially meet criteria.

Version History

Date Published 02.05.03

Materials

Large (MOV) 17 MB
Large (WMV) 17 MB
Small (MOV) 7 MB
Small (WMV) 7 MB
Transcript (PDF) 12 KB

Explore Related Content

Other Related Resources

Showing of
Image from the interactive
Click & Learn
DNA Sequence Assembly
Image from the video representing DNA sequence as strips of paper
Animations
Sanger Sequencing
Image from the video representing DNA sequences as strips of paper
Animations
Shotgun Sequencing
Image from the activity
Case Studies
DNA Profiling Activity
Image from the video
Animations
Coding Sequences in DNA
Image from the interactive
Click & Learn
Virochip DNA Microarray
Image from the video illustrating metabarcoding
Clips
Metabarcoding
Image from the interactive
Click & Learn
How to Analyze DNA Microarray Data
Image of the virtual lab
Virtual Labs
Bacterial Identification Virtual Lab
Photo of Charles Sawyers from the video
Clips
DNA Sequence Technology Improves Cancer Treatment
HHMI BioInteractive
  • Facebook
  • Instagram
  • Twitter
  • YouTube
  • Newsletter Signup
  • HHMI.org
  • Terms of Use
  • Privacy Policy
  • Accessibility