Cytotoxic T Cell in Action
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Description
This video shows real footage of a cytotoxic T cell killing a cell infected by a pathogen.
When a cytotoxic T cell finds an infected cell, it forms a connection to that cell called a cytoplasmic bridge. Through this bridge, the cytotoxic T cell delivers enzymes that create holes in the infected cell’s membrane, killing the cell. This video shows the process recorded by video microscopy.
This clip is from a 2007 Holiday Lecture Series, AIDS: Evolution of an Epidemic.
Key Terms
CD8, cytotoxic T lymphocyte (CTL), granzyme, immune cell, serine esterase, white blood cell
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