CRISPR-Cas9 Mechanism & Applications

Topic
Resource Type
Description
This interactive module explores how CRISPR-Cas9 technology works and the many ways in which scientists are using it in their research.
Since it was first described in 2012, CRISPR-Cas9 (often shortened to “CRISPR”) has generated much interest and excitement. This Click & Learn allows students to explore and learn about a biotechnology tool that is at the forefront of scientific research and hear directly from leading scientists about how they use CRISPR. The Click & Learn comprises a self-paced interactive animation and a series of short videos of various scientists who are using CRISPR-Cas9 technologies for basic research, medical, and agricultural applications.
The “Web Assets” ZIP file contains the full animation and a set of related images and GIFs for use on social media, in the classroom, and for presentations to the public. Please credit HHMI BioInteractive if you use them.
Estimated Time
Key Terms
base pairing, cleavage, complementary sequence, DNA repair, enzyme, guide RNA, homology-directed repair (HDR), laboratory technique, nonhomologous end joining (NHEJ), nuclease
Terms of Use
Please see the Terms of Use for information on how this resource can be used.
Accessibility Level (WCAG compliance)
Version History
NGSS (2013)
HS-LS1.A, HS-LS3.A
AP Biology (2019)
IST-1.K, IST-1.L, IST-1.P, IST-2.A, IST-2.E, IST-4.B
IB Biology (2016)
2.6, 2.7, 3.5, 7.2, B.4, B.5
VIsion and Change (2009)
CC2, CC3