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Cancer and Cell Fate in the Intestinal Epithelium

Topic
  • Cell Biology
  • Cell Cycle
  • Anatomy & Physiology
  • Metabolism & Nutrition
Resource Type
  • Videos
  • Animations
Level
High School — AP/IBCollege
Duration
00:02:17
Favorited By
11 Users
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View in Spanish
Description

This animation shows how disrupting cellular processes in the intestines can lead to colon cancer.

Differentiation and maturation are normal processes in intestinal epithelial cells. When these processes are disrupted by mutations, however, tumors can form. This animation illustrates how a mutation in a gene called APC, which is involved in cellular differentiation, affects the fate of undifferentiated stem cells and results in tumor growth.

Depending on students’ backgrounds, it may be helpful to pause the animation at various points to discuss different cell types and other features.

Details
Key Terms

cell division, cellular differentiation, colon, intestine, stem cell, tumor, tumor suppressor, villus

Terms of Use

Please see the Terms of Use for information on how this resource can be used.

Version History
Date Published 04.30.14
Date Updated 06.02.20
Curriculum Connections
NGSS (2013)

HS-LS1.B

AP Biology (2019)

IST-1, IST-2, IST-3

IB Biology (2016)

1.1

Vision and Change (2009)

CC2

Materials
HD (MP4) 65 MB
HD (WMV) 60 MB
SD (MP4) 17 MB
SD (WMV) 15 MB
Transcript (PDF) 13 KB
Spanish Dub (Español) (MP4) 35 MB
Transcript - Español (PDF) 189 KB

Educator Tips

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Cancer and Cell Fate
Keri Shingleton explains how she uses the BioInteractive animation on cancer and cell fate to spark curiosity in her students and encourage exploration of a topic.
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