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Cancer and Cell Fate in the Intestinal Epithelium

Topic

  • Cell Biology
  • Cell Cycle
  • Anatomy & Physiology
  • Metabolism & Nutrition

Resource Type

  • Videos
  • Animations

Level

High School — AP/IBCollege

Duration

00:02:17
Saved By
16 Users
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View in Spanish

Description

This animation shows how disrupting cellular processes in the intestines can lead to colon cancer.

Differentiation and maturation are normal processes in intestinal epithelial cells. When these processes are disrupted by mutations, however, tumors can form. This animation illustrates how a mutation in a gene called APC, which is involved in cellular differentiation, affects the fate of undifferentiated stem cells and results in tumor growth.

Depending on students’ backgrounds, it may be helpful to pause the animation at various points to discuss different cell types and other features.

Taken from the 2013 Holiday Lectures on Science.

Key Terms

cell division, cellular differentiation, colon, intestine, stem cell, tumor, tumor suppressor, villus

Terms of Use

Please see the Terms of Use for information on how this resource can be used.

Accessibility Level (WCAG compliance)

Video files meet criteria. Spanish files meet criteria.

Version History

Date Published 04.30.14
Date Updated 06.02.20

NGSS (2013)

HS-LS1.B

AP Biology (2019)

IST-1, IST-2, IST-3

IB Biology (2016)

1.1

Vision and Change (2009)

CC2

Materials

HD (MP4) 65 MB
HD (WMV) 60 MB
SD (MP4) 17 MB
SD (WMV) 15 MB
Transcript (PDF) 13 KB
Spanish Dub (Español) (MP4) 35 MB
Transcript - Español (PDF) 189 KB

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Cancer and Cell Fate

Keri Shingleton explains how she uses the BioInteractive animation on cancer and cell fate to spark curiosity in her students and encourage exploration of a topic.
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