Alzheimer’s Disease: Piecing Together the Evidence
This interactive module allows students to examine evidence from brain anatomy, tissue histology, and genetic studies to identify possible targets for the treatment of Alzheimer’s disease.
Alzheimer’s disease affects one out of nine individuals over the age of 65 in the United States alone, but currently has no treatment. In this Click & Learn, students analyze and interpret evidence from different fields to learn about the biology of Alzheimer’s disease and the molecules it involves. They also engage in scientific questioning, data analysis, and evaluation of evidence to suggest possible treatments.
The accompanying worksheet guides students’ exploration.
Student Learning Targets
- Analyze data and evaluate evidence to build an understanding of the biological mechanism of Alzheimer’s disease.
- Identify the biological molecules associated with Alzheimer’s disease and use this information to suggest a possible treatment.
aging, amyloid precursor protein (APP), autosomal dominant inheritance, beta amyloid (β-amyloid), brain, dementia, drug development, memory, pedigree chart, tau protein
HS-LS1-2, HS-LS3-1; SEP1, SEP4
IST-1.I, IST-1.O, IST-1.P, IST-2.E, IST-3.A, IST-4.A, IST-4.B, SYI-1.B, SYI-1.C; SP1, SP2, SP3
2.6, 3.1, 3.4, B.4
ELA.RST.9-12.2, ELA.RST.9–12.4, ELA.WHST.9-12.9
CC3, CC5; DP1, DP6